Welcome to the miRNASNP database

MicroRNAs (miRNAs) are endogenous and regulatory non-coding RNAs by targeting mRNAs for cleavage or translational repression. SNPs in pre-miRNAs or target sites will affect miRNA function and be related with diseases or biological processes. miRNASNP aims to provide a resource of the miRNA-related SNPs, which includes SNPs in pre-miRNAs of human and other species, and target gain and loss by SNPs in miRNA seed regions or 3'UTR of target mRNAs.

New features in miRNASNP V2

  1. Potential functional SNPs increase to 365994;
  2. Experimental validated miRNA-gene interaction;
  3. Expression and correlation of miRNAs and genes;
  4. Minor allele frequency (MAF) and GWAS information of SNPs;
  5. Multiple filters to prioritize functional SNP selection;
  6. Tools to predict the effect of miRNA related SNP.

Database

Publication for citation

An update of miRNASNP database for better SNP selection by GWAS data, miRNA expression and online tools
Jing Gong, Chunjie Liu, Wei Liu, Yuliang Wu, Zhaowu Ma, Hu Chen, and An-Yuan Guo.    Database published online April 15, 2015, 2015: bav029
Genome-Wide Identification of SNPs in MicroRNA Genes and the SNP Effects on MicroRNA Target Binding and Biogenesis
J Gong, Y Tong, HM Zhang, K Wang, T Hu, G Shan, J Sun*, and AY Guo*.    Human Mutation 2011;DOI: 10.1002/humu.21641