Welcome to TCRdb

Introduction for TCRdb

TCRdb is a comprehensive T-cell receptor (TCR) database, the TCR on the surface of T cells recognize antigen and participate in the activation of T cells in immune response. The diversity and antigen specificity of TCRs are mainly determined by the high hypervariable complementarity-determining region 3 (CDR3). TCRdb contains processed sequences of TCRs CDR3 beta chain of human with different phenotypes. We provide an easy-to-use interface to query and browse the database, which will make TCRdb a very useful resource in T cell related researches.

What can users do in TCRdb

• Search identical/similar CDR3 sequences.
• Find disease/tissue/cell-specific TCR CDR3 sequences.
• Browse TCR CDR3 sequences in different diseases and tissues.

Citation

TCRdb: a comprehensive database for T-cell receptor sequences with powerful search function
Si-Yi Chen, Tao Yue, Qian Lei*, and An-Yuan Guo*. Nucleic Acids Research. (2021)