AnimalTFDB is a comprehensive database including classification and annotation of genome-wide transcription factors (TFs) and transcription cofactors in 183 animal genomes. In AnimalTFDB v4.0, there are total 270k TFs which are further classified into 73 families and six categories based on their DNA-binding domain (DBD). Meanwhile, there are also 150k cofactors classified into 82 families and six categories.
To better understand animal transcription factors and cofactors, we annotated them in multiple aspects, including gene expression, basic gene information, paralog and ortholog information, transcription factor binding sites, pathway, phenotype, gene ontology, post-translational modification and mutation information. Overall, AnimalTFDB will provide researchers with essential and detailed information about animal transcription factors and cofactors.
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If necessary, the AnimalTFDB v3.0 is here: