All TFs contain DNA-binding domains (DBDs), through which to bind to specific DNA sequences and regulating gene transcription. According to the conserved DBDs, TFs were classified into 70 families and a class named "Others" which includes some orphan TFs. The 70 families were then merged into 6 groups according to TRANSFAC database and literatures.
e.g. ENSG00000141510; 7157; TP53; P53, TRP53